吉庆刚
个人简介(300-500字)
2005.09~ 澳门新莆京游戏网站 副教授
2002.09~2005.08 中科院上海药物研究所 药物化学 理学博士
1999.09~2002.06 重庆医科大学 药物化学 医学硕士
1992.09-1996.06 桂林理工大学 应用化学 学士
联系方式
Jiqing@swu.edu.cn
研究方向
1. 药物化学: 以几丁质合成酶为作用靶点的抗真菌小分子化合物的设计、合成和初步的活性筛选研究。
2. 药物中间体及精细化学品的合成工艺开发
代表性论文、专著和专利(不超过20项)
1. Baihui Li,Yangli Shen,Hu Wu,Xiaobo Wu,Lvjiang Yuan,Qinggang Ji*, Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1H)-quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents. Eur. J. Med. Chem. 2020, 195:112278
2. Bing Li, Kaiyuan Wang, Rui Zhang, Baihui Li, Yangli Shen, Qinggang Ji *, Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. Eur. J. Med. Chem. 2019, 182:111669
3. Qinggang Ji*, Qiao Deng, Bing Li, Baihui Li, Yangli Shen. Design, synthesis and biological evaluation of novel 5-(piperazin-1-yl)quinolin-2(1H)-one derivatives as potential chitin synthase inhibitorsand antifungal agents. Eur. J. Med. Chem. 2019, 180: 204-212
4. Qinggang Ji*, Zhiqiang Ge, Zhixing Ge, Kaizhi Chen, Hualong Wu, Xiaofei Liu, Yanrong Huang, Lvjiang Yuan, Xiaolan Yang, Fei Liao .Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. Eur. J. Med. Chem. 2016, 108:166-176
5. Zhiqiang Ge, Qinggang Ji*, Chunyan Chen, Qin Liao, Hualong Wu, Xiaofei Liu, Yanrong Huang, Lvjiang Yuan, Fei Liao. Synthesis and biological evaluation of novel 3-substituted amino-4- hydroxylcoumarin derivatives as chitin synthase inhibitors and antifungal agents. J Enzyme Inhib Med Chem. 2016, 31(2):219-228
专利申请及授权:
6. 吉庆刚,李兵。二氮杂螺癸烷哌啶甲酰胺类化合物制备和应用。申请号:201910070042.5
7. 吉庆刚,黄焱容。亚胺螺环哌啶类化合物的合成及应用。申请号:201910029437.0
8. 吉庆刚, 杨丹。1-甲基-2,4-喹唑啉二酮衍生物及其制备方法和应用。申请号:201210554027.6。授权专利
9. 吉庆刚, 杨丹。3-取代-1-甲基-2,4-喹唑啉二酮类化合物及其制备方法和应用。申请号:201210164365.9, 授权专利
10. 吉庆刚, 刘洪彬。N-乙酰-喹啉-2(1H)酮类化合物及其制备方法和应用。 申请号:201210089609.1, 授权专利
11. 吉庆刚,刘洪彬。5-氨基喹啉-2(1H)酮类化合物及其合成方法和用途。申请号:201110363726.8,授权专利
12. 吉庆刚, 张玉斌。抗真菌的取代吡唑啉化合物及其制备方法和应用。申请号:200910103388.7, 授权专利