刘堂林
教授
个人简介(300-500字)
刘堂林,教授、硕士研究生导师。2008年(本科)毕业于南开大学,2014年(博士)毕业于武汉大学化学与分子科学学院,师从王春江教授,主要研究催化不对【3+2】环加成合成手性螺四氢吡咯化合物;在此期间,在新泽西州立大学张绪穆教授课题组访问一年,研究催化不对称氢化反应。随后在新加坡国立大学赵宇教授课题组做博士后研究,主要研究烯丙基醇类化合物的催化不对称异构化反应。自2017年9月起加入澳门新莆京游戏网站开展独立科研工作,教授、硕士生导师。已发表包括J. Am. Chem. Soc.、Angew. Chem. Int. Ed.,Chem. Sci.、Org. Lett.等学术期刊论文20余篇。
个人主页
https://www.x-mol.com/groups/Liu_Tanglin
联系方式
e-mail: liuschop@swu.edu.cn
Tel: 18996404591 QQ: 329381296
研究方向
本课题组主要研究的是金属有机化学。主要从事金属催化的有机合成方法学、不对称合成方法学的开发及应用研究;重要有机化合物分子的手性合成研究。
目前的主要研究方向为:
1) 过渡金属催化的“借氰”反应
2) 过渡金属催化的“借芳基”反应
3) 烯丙基醇类化合物与鎓离子的新型反应研究
代表性论文、专著和专利(不超过20项)
1. Cyano-Borrowing: Titanium-Catalyzed Direct Amination of Cyanohydrins with Amines and Enantioselective Examples.
Liu, T.-L.*; Li, Z.-F.; Tao, J.; Li, Q.-H.; Li, W.-F.; Li, Q.; Ren, L.-Q.; Peng, Y.-G.*, Chem. Commun. 2020, 56, 651-654.
2. Cyano-borrowing reaction: nickel-catalyzed direct conversion of cyanohydrins and aldehydes/ketones to β-cyano ketone.
Li, Z.-F.; Li, Q.; Ren, L.-Q.; Li, Q.-H.; Peng, Y.-G.*; Liu, T.-L.*, Chem. Sci. 2019, 10 (22), 5787-5792.
3. Titanium-Catalyzed Cyano-Borrowing Reaction for the Direct Amination of Cyanohydrins with Ammonia.
Li, Q.-H.*; Li, Z.-F.; Tao, J.; Li, W.-F.; Ren, L.-Q.; Li, Q.; Peng, Y.-G.; Liu, T.-L.*, Org. Lett. 2019, 21 (20), 8429-8433.
4. Rhodium-Catalyzed Enantioconvergent Isomerization of Homoallylic and Bishomoallylic Secondary Alcohols.
Huang, R.-Z.; Lau, K. K.; Li, Z.; Liu, T.-L.*; Zhao, Y.*, J. Am. Chem. Soc. 2018, 140 (44), 14647-14654.
5. Pd-Catalyzed Enantioselective [6+4] Cycloaddition of Vinyl Oxetanes with Azadienes to Access Ten-Membered Heterocycles.
Wang, Y.-N.; Yang, L.-C.; Rong, Z.-Q.; Liu, T.-L.; Liu, R.; Zhao, Y., Angew. Chem., Int. Ed. 2018, 57 (6), 1596-1600.
6. Rhodium-Catalyzed Enantioselective Isomerization of Secondary Allylic Alcohols to Access Ketones with a-Tertiary Stereocenter.
Tang-Lin Liu, Teng Wei Ng, Yu Zhao* J. Am. Chem. Soc. 2017, 139, 3643-3646.
7. Divergent Reactivities in Fluoronation of Allylic Alcohols: Synthesis of Z-Fluoroalkenes via Carbon-Carbon Bond Cleavage.
Tang-Lin Liu, Ji’En. Wu, Yu. Zhao* Chem. Sci. 2017, 8, 3885-3890.
8. Copper(I)-Catalyzed One-Pot Sequential [3+2]/[8+2] Annulations for Highly (Z)-Selective Construction of Heterocyclic Diazabicyclo[5.3.0]decatrienes.
Tang-Lin Liu#, Qing-Hua Li#, Liang Wei, Yong Xiong, Chun-Jiang Wang*.
Adv. Synth. Catal. 2017, 359, 1854-1859. (IF: 5.646) (#共同一作)
9. Catalytic Asymmetric Construction of Spiro Pyrrolidines With Contiguous Quaternary Centers via 1,3-Dipolar Cycloaddition of Azomethine Ylides
Tang-Lin Liu, Qing-Hua Li, Zhao-Lin He, Jia-Wei Zhang, Chun-Jiang Wang*
Chinese. J. Catal. 2015, 36, 68-77.
10. Synthesis of Chiral Aliphatic Amines through Asymmetric Hydrogenation.
Tang-Lin Liu, Chun-Jiang. Wang,* Xumu. Zhang*.
Angew. Chem., Int. Ed. 2013, 52, 8416-8419.
11. Catalytic Enantioselective Desymmetrization of Meso Cyclic Anhydrides via Iridium-Catalyzed Hydrogenation.
Tang-Lin Liu, Wei. Li, Huilin. Geng, Chun-Jiang. Wang,* Xumu. Zhang*.
Org. Lett. 2013, 15, 1740-1743.