（姓名）梁文斌

（职称、头衔）  教授、博导

个人简介（300-500字）

梁文斌（1982.10-）男，博士，教授，博导，山西交城人。2004年获澳门新莆京游戏网站化学专业学士学位，2008年获澳门新莆京游戏网站分析化学专业硕士学位，2017年获澳门新莆京游戏网站分析化学专业博士学位。2008年7月至2018年1月在中国人民解放军第三军医大学检验系从事临床生物化学及抗体工程教学科研以及生物传感技术及器件研究工作；期间于2012年3月至2013年9月以“苗圃工程”赴美国亚利桑那州立大学交流访问；2018年2月经特别评聘于澳门新莆京游戏网站工作。近年来，主持/主研国家级科研课题10余项，主要研究领域为以功能纳米材料及生物扩增技术为基础的电致化学发光及荧光生物传感技术研究。在新型电致化学发光材料及生物扩增技术方面进行了深入系统的研究，并在电致化学发光、光致电化学及荧光多维分析系统方面进行了广泛的探索。在国际刊物（如《Chem. Sci.》、《Anal. Chem.》、《Theranostics》等）上发表了SCI 收录论文40余篇；授权国家发明专利5项，实用新型专利1项。

联系方式

Tel.: 023-68253172

e-mail: wenbinliangasu@gmail.com; wenbinliang@swu.edu.cn

研究方向

光/电生物传感技术

代表性论文、专著和专利（不超过20项）

1)      Liang WB, Yang MZ, Zhuo Y, Zheng YN, Xiong CY, Chai YQ*, Yuan R*. Competitive method-based electrochemiluminescent assay with protein-nucleotide conversion for ratio detection to efficiently monitor drug resistance of cancer cells. Chemical Science 2016, 7: 7094-7100.

2)      Yang ZZ, Peng X, Yang P, Zhuo Y, Chai YQ, Liang WB*, Yuan R*. A Janus 3D DNA nanomachine for simultaneous and sensitive fluorescence detection and imaging of dual microRNAs in cancer cells. Chemical Science 2020, 11: 8482-8488.

3)      Ming-Li Su, Zhao-Peng Chen, Bei-Bei Ye, Hao-Ran Chen, Ruo Yuan, Ping Li*, and Wen-Bin Liang*. Three-in-One System Based on Multi-Path Nucleic Acid Amplification for Bioanalysis of Pre-miRNA/miRNA and Dicer Activity. Analytical Chemistry 2022, 94: 8258–8266

4)      Zhao-Peng Chen, Peng Yang, Ze-Zhou Yang, Ya-Qin Chai, Ruo Yuan, Ying Zhuo, and Wen-Bin Liang*. One-step Digital Droplets Auto-catalytic Nucleic Acids Amplification with High-throughput Fluorescence Imaging and Droplet Tracking Computation. Analytical Chemistry. 2022, 94, 25, 9166-9175

5)      Yin XR, Yang P, Zhang HM, Zhu QJ, Yuan R, Li Y, Liang WB*. Hydrophobic-Driven Electrochemiluminescence Enhancement via Target-Induced Self-Enrichment for Ultrasensitive Bioassay. Analytical Chemistry 2020, 92, 15120-15128.

6)      Chen JX, Zhuo Y, Peng X, Chai YQ, Yuan R*, Liang WB*. A Dynamic DNA Nanomachine via Free Walker Movement on Lipid Bilayer for Ultrasensitive Electrochemiluminescent Bioassay. Analytical Chemistry 2019, 91, 14125-14132.

7)      Peng X, Wen ZB, Yang P, Chai YQ, Liang WB*, Yuan R*. Biomimetic 3D DNA Nanomachine via Free DNA Walker Movement on Lipid Bilayers Supported by Hard SiO₂@CdTe Nanoparticles for Ultrasensitive MicroRNA Detection. Analytical Chemistry 2019, 91, 14920-14920.

8)      Liang WB, Fan CC, Zhuo Y, Zheng YN, Xiong CY, Chai YQ*, Yuan R*. Multiparameter analysis-based electrochemiluminescent assay for simultaneous detection of multiple biomarker proteins on a single interface. Analytical Chemistry 2016, 88: 4940-4948.

9)      Liang WB, Zhuo Y, Xiong CY, Zheng YN, Chai YQ*, Yuan R*. Ultrasensitive cytosensor based on self-enhanced electrochemiluminescent ruthenium-silica composite nanoparticles for efficient drug screening with cell apoptosis monitoring. Analytical Chemistry 2015, 87: 12363-12371.

10)  Liang WB, Wang SP, Festa F, Wiktor P, Wang W, Magee M, LaBaer J*, Tao NJ*. Measurement of small molecule binding kinetics on a protein microarray by plasmonic-based electrochemical impedance imaging. Analytical Chemistry 2014, 86: 9860-9865.

11)  Zhao-Peng Chen, Hao-Min Zhang, Peng Yang, Ruo Yuan, Yan Li*, Wen-Bin Liang*. No-nonspecific recognition-based amplification strategy for endonuclease activity screening with dual-color DNA nano-clew. Biosensors and Bioelectronics 2021, 190: 113446

12)  Zhao-Peng Chen, Ming-Li Su, Hao-Ran Chen, Ruo Yuan, Yan Li*, Wen-Bin Liang* Proximity hybridization-induced competitive rolling circle amplification to construct fluorescent dual-sensor for simultaneous evaluation of glycated and total hemoglobin. Biosensors and Bioelectronics. 2022, 202: 113998

13)  Li Y, Xiong Y, Fang LC, Jiang LL, Huang H, Deng J, Liang WB*, Zheng JS*. An electrochemical strategy using multifunctional nanoconjugates for efficient simultaneous detection of Escherichia coli O157: H7 and Vibrio cholerae O1. Theranostics 2017, 4: 935-944.

14)  组装式电化学电极套件. 201922080020.5（2020.09）。

15)  一种电致化学发光免疫传感器的制备、产品、检测与应用，201611131329.7（2018.03）。

      16)一种多功能化的铁钴磁性纳米传感器的制备方法及其产品和应用，201611117355.4（2019.04）。